Iranian Journal of Ceramic Science & Engineering
Volume 8, Issue 4 (2-2020)
2020, 8(4): 91-101 |
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Evaluation of cytotoxicity and mechanical properties of
fluorapatite-45S5 bioactive glass nanocomposite. Iranian Journal of Ceramic Science & Engineering 2020; 8 (4) :91-101
URL: http://ijcse.ir/article-1-742-en.html
URL: http://ijcse.ir/article-1-742-en.html
Abstract: (2545 Views)
The purpose of this study was to fabricate and characterize nanocomposite powder from 45S5 bioactive glass/ fluorapatite. Nanocomposites containing 10, 15 and 20 wt.% of fluorapatite were synthesized by sol-gel method. XRD and FT-IR analyses were used to characterize and evaluate the produced nanocomposites. The results of XRD and FT-IR analysis indicated the successful synthesis of high purity bioactive glass nanocomposites. The results of compressive strength test showed an increase in strength of sample containing 15% fluorapatite. MTT (3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyltetrazolium Bromide) assay was used to evaluate cytotoxicity. The results of this section showed no cytotoxicity of the samples, which showed a decrease in the survival rate after seven days. The lowest survival rate was observed for pure fluorapatite.
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