In this study, the preparation of transparent glass-ceramics with lithium-mica nanocrystals by melt-quenching method was investigated. The influence of Y3+-doping on the luminescence properties of the parent glass and the glass-ceramics was studied. Transparent glass-ceramics, in which a large quantity of lithium-mica with particle size of <50 nm was separated, could be prepared by a suitable heat treatment. The observed emission spectra showed that Y3+ ions in glass and glass-ceramic were emitted blue light. Theses transparent glass-ceramics are promising materials for white LED and laser materials