Iranian Journal of Ceramic Science & Engineering
Volume 8, Issue 2 (9-2019)
2019, 8(2): 29-39 |
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Rhological Behavior of Injectable Bioactive Glass/Gelatin Pastes Used for Bone Replacement. Iranian Journal of Ceramic Science & Engineering 2019; 8 (2) :29-39
URL: http://ijcse.ir/article-1-701-en.html
URL: http://ijcse.ir/article-1-701-en.html
Abstract: (2936 Views)
Injectable pastes are bioactive materials which are used in various forms in the living organism. The bioactivity of these materials are derived from calcium phosphate powder and/or a bio-glass composition. These materials are not individually injectable; however, they will be when suitable polymers such as chitosan, gelatin, sodium alginate, hyaluronic acid, etc. added to the paste. In this research, the authors have tried to prepare a bioactive injectable glass/polymer paste via mixing a sol-gel derived glass powder, based on the SiO2-CaO-P2O5 system, with polymer’s solution of gelatin. The rheological behavior and the injectability of the pastes were also investigated. The results showed that the paste was well-injected; however, it showed an undefined rheological behavior. The maximum viscosity of the paste was 8.88 × 10 Pa.s and it was washed out during it’s immersion in a simulated body fluid with time and reached to approximately 60wt.% of its initial weight after 48h. According to microstructural analysis, mineralogical phase analysis and Fourier Transform IR spectrometry analysis, the paste showed bioactivity after 14 days immersion in SBF solution.
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